Steroid seks

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Steroid seks, juga dikenali sebagai steroid gonad, ialah hormon steroid yang berinteraksi dengan androgen vertebrat atau reseptor estrogen.[1] Kesannya diantara oleh mekanisme genomi yang perlahan menerusi reseptor nukleus serta juga oleh mekanisme bukan genom menerusi reseptor berkait membran dan lata pengisyaratan.[2] Istilah hormon seks hampir selalu merupakan sinonim kepada steroid seks.

Pengeluaran[sunting | sunting sumber]

Steroid seks semula jadi dibuat oleh:

Steroid seks tiruan[sunting | sunting sumber]

There are also many synthetic sex steroids. Synthetic androgens are often referred to as anabolic steroids. Synthetic estrogens and progestins are used in methods of hormonal contraception. Ethinylestradiol is a semi-synthetic estrogen. Specific compounds that have partial agonist activity for steroid receptors, and therefore act in part like natural steroid hormones, are in use in medical conditions that require treatment with steroid in one cell type, but where systemic effects of the particular steroid in the entire organism are only desirable within certain limits[4].

Jenis[sunting | sunting sumber]

Dalam banyak konteks, dua kelas utama steroid seks ialah androgen dan estrogen, dengan terbitan manusia yang paling penting masing-masing merupakan testosteron dan estradiol. Konteks yang lain termasuk progestagen sebagai kelas ketiga steroid seks yang berbeza daripada androgen dan estrogen. Progesteron ialah progestagen yang paling penting serta progestagen tunggal yang wujud secara semula jadi. Umumnya, androgen dianggap sebagai "hormon seks lelaki" kerana mereka mempunyai kesan pemaskulinan, manakala estrogen dan progestagen dianggap "hormon seks perempuan",[5] sungguhpun semua jenis wujud dalam setiap jantina, walau pada tahap yang berbeza.

Steroid seks termasuk:

Lihat juga[sunting | sunting sumber]

Rujukan[sunting | sunting sumber]

  1. Guerriero G. Vertebrate sex steroid receptors: evolution, ligands, and neurodistribution. Ann N Y Acad Sci. 2009 Apr;1163:154-68. Review. PMID: 19456336
  2. Thakur MK, Paramanik V. Role of steroid hormone coregulators in health and disease. Horm Res. 2009;71(4):194-200. Epub 2009 Mar 4. Review. PMID: 19258710
  3. Brook CG. Mechanism of puberty. Horm Res. 1999;51 Suppl 3:52-4. Review. PMID: 10592444
  4. Copland JA, Sheffield-Moore M, Koldzic-Zivanovic N, Gentry S, Lamprou G, Tzortzatou-Stathopoulou F, Zoumpourlis V, Urban RJ, Vlahopoulos SA. Sex steroid receptors in skeletal differentiation and epithelial neoplasia: is tissue-specific intervention possible? Bioessays. 2009 Jun;31(6):629-41. Review. PMID: 19382224
  5. Comparative metabolism of female sex steroids in normal and chronically inflamed gingiva of the dog T. M. A. ElAttar11Department of Biochemistry, University of Missouri-Kansas City School of Dentistry, Kansas City, Missouri, U.S.A. and Department of Periodontology, The Institute for Postgraduate Dental Education, Jönköping, Sweden AND A. Hugoson11Department of Biochemistry, University of Missouri-Kansas City School of Dentistry, Kansas City, Missouri, U.S.A. and Department of Periodontology, The Institute for Postgraduate Dental Education, Jönköping, Sweden1Department of Biochemistry, University of Missouri-Kansas City School of Dentistry, Kansas City, Missouri, U.S.A. and Department of Periodontology, The Institute for Postgraduate Dental Education, Jönköping, Sweden

Pautan luar[sunting | sunting sumber]