Benziltiourasil

Benziltiourasil
Data klinikal
AHFS/Drugs.com	International Drug Names
Kaedah; pemberian	Mulut
Kod ATC	H03BA03 (WHO) ;
Data farmakokinetik
Perkumuhan	Buah pinggang
Pengecam
	Nama IUPAC 1-(1-sikloheksa-2,4-dienilmetil)-7-tia-; 3,5-diazabisiklo[4.1.0]hepta-3,5-dien-2-on;
Nombor CAS	6336-50-1 ;
PubChem CID	685814;
ChemSpider	597542 ;
UNII	PZ35LUM333;
ChEMBL	ChEMBL1491306;
CompTox Dashboard (EPA)	DTXSID30873587 ;
ECHA InfoCard	100.026.106
Data kimia dan fizikal
Formula	C11H10N2OS
Jisim molar	218.27 g·mol−1
Model 3D (JSmol)	Gambar interaktif;
	SMILES S=C1N/C(=C\C(=O)N1)Cc2ccccc2;
	InChI InChI=1S/C11H10N2OS/c14-10-7-9(12-11(15)13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,12,13,14,15) ; Key:PNXBXCRWXNESOV-UHFFFAOYSA-N ;
	(verify)

Benziltiourasil (BTU) ialah sebuah penyediaan antitiroid. Ia merupakan sejenis tioamida, serupa dengan propiltiourasil.

Kesan sampingan[sunting | sunting sumber]

Benziltiourasil telah dikaitkan dengan kesan sampingan, terutamanya vaskulitis dan seterusnya glomerulonefritis positif ANCA, serta kes-kes terpencil kerosakan peparu.^[1]^[2]^[3]^[4]

Rujukan[sunting | sunting sumber]

^ Tieulie N, Huong DL, Andreu M, dll. (2002). "[ANCA associated glomerulonephritis related to benzylthiouracil]". Rev Méd Interne (dalam bahasa French). 23 (10): 853–6. doi:10.1016/S0248-8663(02)00694-X. PMID 12428489.CS1 maint: unrecognized language (link)
^ Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H (2002). "[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]". Rev Méd Interne (dalam bahasa French). 23 (10): 857–61. doi:10.1016/S0248-8663(02)00704-X. PMID 12428490.CS1 maint: unrecognized language (link)
^ Braham A, Houman MH, Rais L, Ben Gborbel I, Lamloum M, Miled M (2004). "[Benzylthiouracil induced ANCA-positive vasculitis]". Presse Médicale (dalam bahasa French). 33 (19 Pt 1): 1331–3. doi:10.1016/S0755-4982(04)98919-1. PMID 15615240.CS1 maint: unrecognized language (link)
^ Thabet F, Sghiri R, Tabarki B, Ghedira I, Yacoub M, Essoussi AS (2006). "ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil". Eur J Pediatr. 165 (7): 435–6. doi:10.1007/s00431-005-0053-4. PMID 16622664.

Rencana berkenaan perubatan ini ialah rencana tunas. Anda boleh membantu Wikipedia dengan mengembangkannya.

[1] Tieulie N, Huong DL, Andreu M, dll. (2002). "[ANCA associated glomerulonephritis related to benzylthiouracil]". Rev Méd Interne (dalam bahasa French). 23 (10): 853–6. doi:10.1016/S0248-8663(02)00694-X. PMID 12428489.CS1 maint: unrecognized language (link)

[2] Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H (2002). "[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]". Rev Méd Interne (dalam bahasa French). 23 (10): 857–61. doi:10.1016/S0248-8663(02)00704-X. PMID 12428490.CS1 maint: unrecognized language (link)

[3] Braham A, Houman MH, Rais L, Ben Gborbel I, Lamloum M, Miled M (2004). "[Benzylthiouracil induced ANCA-positive vasculitis]". Presse Médicale (dalam bahasa French). 33 (19 Pt 1): 1331–3. doi:10.1016/S0755-4982(04)98919-1. PMID 15615240.CS1 maint: unrecognized language (link)

[4] Thabet F, Sghiri R, Tabarki B, Ghedira I, Yacoub M, Essoussi AS (2006). "ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil". Eur J Pediatr. 165 (7): 435–6. doi:10.1007/s00431-005-0053-4. PMID 16622664.

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