Betametason valerat

Betametason valerat
Data klinikal
Nama dagang	Betnovate, Celestoderm, Ecoval 70, Hormezon
Nama lain	Betamethasone 17-valerat
AHFS/Drugs.com	Monograph
Kelas ubat	Kortikosteroid; glukokortikoid
Pengecam
	Nama IUPAC (11β,16β)-9-Fluoro-11,21-dihidroksi-16-metil-3,20-dioksopregna-1,4-dien-17-il valerat;
Nombor CAS	2152-44-5;
PubChem CID	16533;
ChemSpider	15673;
UNII	9IFA5XM7R2;
ChEBI	CHEBI:31277 ;
ChEMBL	ChEMBL1497 ;
CompTox Dashboard (EPA)	DTXSID7022673 ;
ECHA InfoCard	100.016.764
Data kimia dan fizikal
Formula	C27H37FO6
Jisim molar	476.59 g·mol−1
Model 3D (JSmol)	Gambar interaktif;
	SMILES CCCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO;
	InChI InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1 ; Key:SNHRLVCMMWUAJD-SUYDQAKGSA-N ;

Betametason valerat ialah sejenis ester glukokortikoid sintetik. Ia merupakan ester jenis 17-valerat bagi betametason.^[1]^[2] Betametason valerat biasanya digunakan untuk merawat ekzema ringan dengan keberkesanan baik serta peluang kesan sampingan terbitan steroid yang rendah oleh kerana kekuatannya yang lebih rendah dibanding dengan glukokortikoid lain.^[3] Betametason 17-valerat tersedia dalam bentuk krim, salap, losyen dan busa bagi kegunaan kulit.^[3]^[4]^[5]

Rujukan[sunting | sunting sumber]

^ Ly S, Amici JM (2018). "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context. 7: 212539. doi:10.7573/dic.212539. PMC 6104053. PMID 30151017.
^ "Betamethasole valerate". PubChem. U.S. National Library of Medicine.
^ ^a ^b Raveendran, Rekha (2019-11-01). "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America (dalam bahasa Inggeris). 39 (4): 521–533. doi:10.1016/j.iac.2019.07.006. ISSN 0889-8561. PMID 31563186. S2CID 202816063.
^ Payne, Jessica; Habet, Kyle A.; Pona, Adrian; Feldman, Steven R. (2019-08-01). "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology. 18 (8): 756–770. ISSN 1545-9616. PMID 31424707.
^ Duweb, G. A.; Abuzariba, O.; Rahim, M.; al-Taweel, M.; Abdulla, S. A. (2000). "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research. 20 (3–4): 65–68. ISSN 0251-1649. PMID 11314240.

Rencana berkenaan perubatan ini ialah rencana tunas. Anda boleh membantu Wikipedia dengan mengembangkannya.

[1] Ly S, Amici JM (2018). "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context. 7: 212539. doi:10.7573/dic.212539. PMC 6104053. PMID 30151017.

[2] "Betamethasole valerate". PubChem. U.S. National Library of Medicine.

[:0-3] Raveendran, Rekha (2019-11-01). "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America (dalam bahasa Inggeris). 39 (4): 521–533. doi:10.1016/j.iac.2019.07.006. ISSN 0889-8561. PMID 31563186. S2CID 202816063.

[4] Payne, Jessica; Habet, Kyle A.; Pona, Adrian; Feldman, Steven R. (2019-08-01). "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology. 18 (8): 756–770. ISSN 1545-9616. PMID 31424707.

[5] Duweb, G. A.; Abuzariba, O.; Rahim, M.; al-Taweel, M.; Abdulla, S. A. (2000). "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research. 20 (3–4): 65–68. ISSN 0251-1649. PMID 11314240.

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