Sitokrom c

Sitokrom c
Struktur sedia ada
PDB	Pencarian ortolog: PDBe RCSB
Senarai kod PDB
	1J3S, 3NWV, 3ZCF, 3ZOO, 2N9J, 2N9I
Pengecam
Alias	CYCS, CYC, HCS, THC4, cytochrome c, somatic, Cytochrome c, cyt c
Pengecam-pengecam luaran	OMIM: 123970 MGI: 88578 HomoloGene: 133055 GeneCards: CYCS
Kedudukan gen (Manusia)
Kr.	Kromosom 7
Tamat	25,125,260 bp
Corak ekspresi RNA
	Top expressed in
	mucosa of transverse colon; ; rektum; ; right auricle; ; muscle of thigh; ; gastrocnemius muscle; ; prefrontal cortex; ; apex of heart; ; epithelium of colon; ; gonad; ; Ventrikel kiri;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; right kidney; ; tian; ; muscle of thigh; ; esofagus; ; tian; ; Kantung yolka; ; morula; ; superior frontal gyrus; ; tail of embryo;
	More reference expression data
	Rujukan lanjutan untuk data ekspresi
Ontologi gen
Fungsi molekul	protein serine/threonine phosphatase activity; ikatan ion logam; Pengikatan protein plasma; heme binding; electron transfer activity;
Komponen sel	cytosol; protein phosphatase type 2A complex; Mitokondrion; mitochondrial inner membrane; respirasome; nukleus sel; mitochondrial intermembrane space;
Proses biologi	mitochondrion organization; intrinsic apoptotic signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; Respirasi sel; protein dephosphorylation; mitochondrial electron transport, cytochrome c to oxygen; proses apoptosis; mitochondrial electron transport, ubiquinol to cytochrome c; cellular response to oxidative stress;
	Sumber:Amigo / QuickGO
Ortolog
	54205
	13063
	ENSG00000172115
	ENSMUSG00000063694
	P99999
	P62897
	NM_018947
	NM_007808
	NP_061820
	NP_031834
	Wikidata
Papar/Sunting data manusia	Papar/Sunting data mencit

Kompleks sitokrom (juga dikenali sebagai sitokrom c atau sit c sahaja) merupakan sejenis protein hem yang boleh dijumpai pada membran mitokondria dalam. Ia tergolong dalam keluarga sitokrom c protein. Sitokrom c adalah protein larut air yang sangat tinggi, tidak seperti sitokrom yang lain dengan keterlarutan kira-kira 100 g/L dan merupakan komponen penting dalam rantaian pengangkutan elektron di mana ia membawa satu elektron. Ia juga mampu menjalani proses pengoksidaan dan penurunan, tetapi tidak mengikat oksigen. Ia menghantar elektron diantara kompleks III (Koenzim Q – sit c reduktase) dan IV (Sit c oksidase). Pada manusia, sitokrom c dikodkan oleh gen CYCS.^[4]^[5]

Rujukan

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172115 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: cytochrome c".
^ Tafani M, Karpinich NO, Hurster KA, Pastorino JG, Schneider T, Russo MA, Farber JL (Mac 2002). "Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition". J. Biol. Chem. 277 (12): 10073–82. doi:10.1074/jbc.M111350200. PMID 11790791.CS1 maint: multiple names: authors list (link)

Pautan luar

Protein sitokrom c
Cytochrome+c di Tajuk Subjek Perubatan (MeSH) Perpustakaan Perubatan Negara Amerika Syarikat

Rencana biokimia ini ialah rencana tunas. Anda boleh membantu Wikipedia dengan mengembangkannya.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000172115 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: cytochrome c".

[pmid11790791-5] Tafani M, Karpinich NO, Hurster KA, Pastorino JG, Schneider T, Russo MA, Farber JL (Mac 2002). "Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition". J. Biol. Chem. 277 (12): 10073–82. doi:10.1074/jbc.M111350200. PMID 11790791.CS1 maint: multiple names: authors list (link)

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