François Jacob

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François Jacob (17 Jun 1920 - 19 April 2013) ialah ahli biologi Perancis yang, bersama-sama dengan Jacques Monod, memulakan idea bahawa kawalan tahap enzim dalam semua sel berlaku melalui pengawalan transkripsi. Beliau berkongsi Hadiah Nobel dalam Perubatan 1965 dengan Jacques Monod dan André Lwoff.[1][2][3][4]

Rujukan[sunting | sunting sumber]

  1. ^ Morange, Michel (2013). "François Jacob (1920–2013) French freedom fighter who helped to uncover how genes are regulated". Nature. 497 (7450): 440. Bibcode:2013Natur.497..440M. doi:10.1038/497440a. PMID 23698437. 
  2. ^ Jacob, F.; Girard, M. (1998). "Andre Michel Lwoff. 8 May 1902–30 September 1994". Biographical Memoirs of Fellows of the Royal Society. 44: 255–263. doi:10.1098/rsbm.1998.0017. ISSN 0080-4606. PMID 11623983. 
  3. ^ "Nobel-winning biologist Francois Jacob dies at 92". The Raw Story. Dicapai 2013-04-22. 
  4. ^ Morange, Michel (2017). "François Jacob. 17 June 1920 – 19 April 2013". Biographical Memoirs of Fellows of the Royal Society. 63: 345–361. doi:10.1098/rsbm.2016.0021. ISSN 0080-4606. 

Bibliografi[sunting | sunting sumber]

  • Jacob, François; E. L. Wollman. Sexuality and the Genetics of Bacteria. Academic Press, 1961 OCLC 251900319
  • Jacob, François. The Possible & The Actual. Pantheon Books, 1982 ISBN 9780295958880
  • Jacob, François. The Statue Within: An Autobiography by, translated from the 1987 French edition by Franklin Philip. Basic Books, 1988. ISBN 978-0-465-08223-0; new edition: 9780879694760
  • Jacob, François. The Logic of Life. translated from the 1976 French edition by Princeton University Press, 1993 ISBN 0394472462
  • Jacob, François. Of Flies, Mice and Men, translated from the French edition and published by Harvard University Press, 1998 ISBN 9780674631113
  • Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J.; Edelstein, S. (2005). "The operon: A group of genes with expression coordinated by an operator. C.R.Acad. Sci. Paris 250 (1960) 1727–1729". Comptes Rendus Biologies. 328 (6): 514–520. doi:10.1016/j.crvi.2005.04.005. PMID 15999435. 
  • Ullmann, A.; Jacob, F.; Monod, J. (1968). "On the subunit structure of wild-type versus complemented beta-galactosidase of Escherichia coli". Journal of Molecular Biology. 32 (1): 1–13. doi:10.1016/0022-2836(68)90140-X. PMID 4868117. 
  • Ullmann, A.; Jacob, F.; Monod, J. (1967). "Characterization by in vitro complementation of a peptide corresponding to an operator-proximal segment of the beta-galactosidase structural gene of Escherichia coli". Journal of Molecular Biology. 24 (2): 339–343. doi:10.1016/0022-2836(67)90341-5. PMID 5339877. 
  • Ullmann, A.; Perrin, D.; Jacob, F.; Monod, J. (1965). "Identification, by in vitro complementation and purification, of a peptide fraction of Escherichia coli beta-galactosidase". Journal of Molecular Biology. 12 (3): 918–923. doi:10.1016/S0022-2836(65)80338-2. PMID 4285628. 
  • Willson, C.; Perrin, D.; Cohn, M.; Jacob, F.; Monod, J. (1964). "Non-Inducible Mutants of the Regulator Gene in the "lactose" System of Escherichia Coli". Journal of Molecular Biology. 8 (4): 582–592. doi:10.1016/S0022-2836(64)80013-9. PMID 14153528. 
  • Jacob, F.; Ullman, A.; Monod, J. (1964). "The Promotor, A Genetic Element Necessary to the Expression of an Operon". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 258: 3125–3128. PMID 14143651. 
  • Jacob, F.; Monod, J. (1964). "Biochemical and Genetic Mechanisms of Regulation in the Bacterial Cell". Bulletin de la Société de Chimie Biologique. 46: 1499–1532. PMID 14270538. 
  • Monod, J.; Changeux, J.; Jacob, F. (1963). "Allosteric proteins and cellular control systems". Journal of Molecular Biology. 6 (4): 306–329. doi:10.1016/S0022-2836(63)80091-1. PMID 13936070. 
  • Jacob, F.; Sussman, R.; Monod, J. (1962). "On the nature of the repressor ensuring the immunity of lysogenic bacteria". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 254: 4214–4216. PMID 14036499. 
  • Jacob, F.; Monod, J. (1961). "Genetic regulatory mechanisms in the synthesis of proteins". Journal of Molecular Biology. 3 (3): 318–356. doi:10.1016/S0022-2836(61)80072-7. PMID 13718526. 
  • Monod, J.; Jacob, F. (1961). "Teleonomic mechanisms in cellular metabolism, growth, and differentiation". Cold Spring Harbor Symposia on Quantitative Biology. 26: 389–401. doi:10.1101/sqb.1961.026.01.048. PMID 14475415. 
  • Perrin, D.; Jacob, F.; Monod, J. (1960). "Induced biosynthesis of a genetically modified protein not presenting affinity for the inductor". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 251: 155–157. PMID 13734531. 
  • Buttin, G.; Jacob, F.; Monod, J. (1960). "Constituent synthesis of galactokinase following the development of lambda bacteriophages in Escherichia coli K 12". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 250: 2471–2473. PMID 13806544. 
  • Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J. (February 1960). "L'opéron : groupe de gènes à expression coordonnée par un opérateur" [Operon: a group of genes with the expression coordinated by an operator] (PDF). Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences (Facsimile version reprinted in 2005). 250 (6): 1727–1729. ISSN 0001-4036. PMID 14406329. 
  • Jacob, F.; Monod, J. (1959). "Genes of structure and genes of regulation in the biosynthesis of proteins". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 249: 1282–1284. PMID 14406327. 
  • Pardee, A.; Jacob, F.; Monod, J. (1958). "The role of the inducible alleles and the constitutive alleles in the synthesis of beta-galactosidase in zygotes of Escherichia coli". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 246 (21): 3125–3128. PMID 13547552. 
  • Jacob, F.; Torriani, A.; Monod, J. (1951). "Effect of ultraviolet rays on the biosynthesis of galactosidase and on the multiplication of T2 bacteriophage in Escherichia coli". Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 233 (20): 1230–1232. PMID 14905606. 

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